@drpjm
Did you close and re-open Isadora? It won't remap the python environment until that is done.
I assume you have watched these tutorials: Using the Pythoner Actor – Do More in Isadora with Python - YouTube
NOTE: Python is not initialized in Isadora until a Pythoner actor is added to the project. You can update the 'environment activation file' and restart Isadora, and the Python Virtual Environment setting under the Help menu will appear GRAYED OUT & (Awaiting Activation) until the Pythoner actor is added to the project.