In my setup (on my desk, it's a M-Audio 2626), if I put "optimize" on "interactive", if I activate "snd out", I can change output on my sound card, changing "snd out" to "e1-2", "e3-4", "e5-6" or "e7-8".
see pictures
0afb4a-output1-2.jpg c2490d-output3-4.jpg