@CitizenJoe I know you have experience making multiple graphics cards work together, and have had success using these configurations. Please feel free to share your knowledge about these configurations. In no way do I want to limit the sharing of techniques here :)
I have also had success with these configs, having had 3 cards working well in one machine running Isadora. In my case, I had 1 decent GTX card as my Isadora card, and 2 very inexpensive cards (all nVidia) connected for additional outputs. This config was good in that I had many physical outputs all seen as displays by the system. Only the GTX GPU was used for processing. For output, the texture was pulled back and passed to the cheap cards (that's why the cheap cards were great).
The downsides:
- a lot of overhead pulling the textures down and passing them to the other cards (very much like the BlackMagic option) this allowed decent framerates as long as I wasn't doing much processing.. it dropped fast when doing anything more than playback (this was running on an older machine as well).
- mostly untested, and not supported.